Ariela Benigni Selected Research

nephrin

1/2022	Empagliflozin protects glomerular endothelial cell architecture in experimental diabetes through the VEGF-A/caveolin-1/PV-1 signaling pathway.
1/2020	Protective Effects of Human Nonrenal and Renal Stromal Cells and Their Conditioned Media in a Rat Model of Chronic Kidney Disease.
7/2013	Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway.
11/2009	Unlike each drug alone, lisinopril if combined with avosentan promotes regression of renal lesions in experimental diabetes.
5/2008	Primer: strategies for identifying genes involved in renal disease.
1/2006	Pathophysiologic implications of reduced podocyte number in a rat model of progressive glomerular injury.
6/2004	Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy.
3/2004	Changes in glomerular perm-selectivity induced by angiotensin II imply podocyte dysfunction and slit diaphragm protein rearrangement.
7/2003	Targeted downregulation of extracellular nephrin in human IgA nephropathy.
5/2001	Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis.

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Ariela Benigni Research Topics

Disease

33	Proteinuria 12/2021 - 05/2001
23	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 07/2003
12	Inflammation (Inflammations) 01/2020 - 10/2003
12	Kidney Diseases (Kidney Disease) 01/2020 - 09/2002
12	Fibrosis (Cirrhosis) 01/2020 - 02/2006
10	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 11/2007
10	Chronic Renal Insufficiency 01/2020 - 01/2007
9	Hypertension (High Blood Pressure) 01/2020 - 09/2002
8	Albuminuria 01/2022 - 02/2010
8	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 07/2010
8	Disease Progression 01/2021 - 07/2003
7	Type 2 Diabetes Mellitus (MODY) 01/2020 - 11/2011
6	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2019 - 05/2001
5	COVID-19 01/2022 - 01/2020
5	Thrombosis (Thrombus) 01/2022 - 01/2002
5	Glomerulonephritis 01/2021 - 06/2006
5	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2018 - 05/2008
4	Atypical Hemolytic Uremic Syndrome 01/2022 - 01/2019
4	Heart Failure 12/2019 - 12/2002
4	Neoplasms (Cancer) 01/2018 - 04/2000
4	Chronic Kidney Failure (Chronic Renal Failure) 07/2013 - 03/2007
3	Hemolytic-Uremic Syndrome 01/2022 - 12/2006
3	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 12/2021 - 05/2008
3	IGA Glomerulonephritis (IGA Nephropathy) 06/2017 - 07/2003
3	Lupus Nephritis 06/2017 - 05/2007
3	Sclerosis 01/2016 - 01/2006
2	Rare Diseases (Rare Disease) 01/2022 - 01/2021
2	Anemia 01/2021 - 05/2012
2	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 01/2021 - 01/2018
2	Reperfusion Injury 01/2020 - 08/2011
2	Hypertrophy 12/2019 - 01/2006
2	Microvascular Rarefaction 10/2019 - 11/2012
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 07/2018 - 01/2015
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 01/2016
2	Cicatrix (Scar) 11/2014 - 01/2004
2	Body Weight (Weight, Body) 03/2013 - 12/2009
2	Delayed Graft Function 08/2011 - 05/2005
2	Ischemia 10/2009 - 05/2005
2	Pre-Eclampsia (Preeclampsia) 01/2007 - 03/2004

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2001
13	Angiotensin IIIBA 01/2020 - 05/2001
11	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2019 - 07/2003
10	nephrinIBA 01/2022 - 05/2001
9	Sirtuin 3IBA 01/2020 - 01/2010
8	Complement System Proteins (Complement)IBA 01/2022 - 01/2019
7	Lisinopril (Prinivil)FDA LinkGeneric 01/2020 - 05/2001
6	AntibodiesIBA 01/2019 - 07/2003
6	Pharmaceutical PreparationsIBA 07/2018 - 01/2007
5	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2019 - 07/2003
5	Cisplatin (Platino)FDA LinkGeneric 10/2017 - 11/2007
5	MicroRNAs (MicroRNA)IBA 06/2017 - 09/2012
4	Biomarkers (Surrogate Marker)IBA 01/2019 - 02/2010
4	Streptozocin (Streptozotocin)FDA Link 01/2016 - 01/2006
4	Endothelins (Endothelin)IBA 01/2011 - 12/2002
4	Transforming Growth Factor beta (TGF-beta)IBA 03/2007 - 07/2003
3	Complement Factor H (Factor H)IBA 01/2019 - 01/2019
3	SirtuinsIBA 01/2018 - 05/2011
3	Endothelin-1 (Endothelin 1)IBA 03/2015 - 09/2003
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2013 - 01/2004
2	NestinIBA 01/2022 - 12/2009
2	Shiga Toxin (Shigella Toxin)IBA 01/2022 - 12/2006
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2021 - 01/2018
2	eculizumab FDA Link 01/2021 - 01/2019
2	Erythropoietin FDA Link 01/2021 - 05/2012
2	CollagenIBA 01/2020 - 01/2012
2	Oxygen (Dioxygen)IBA 01/2020 - 05/2012
2	AntigensIBA 01/2020 - 08/2011
2	LigandsIBA 10/2019 - 10/2009
2	Peptides (Polypeptides)IBA 10/2019 - 01/2012
2	Phospholipase A2 ReceptorsIBA 01/2019 - 10/2015
2	Adenosine Triphosphate (ATP)IBA 01/2018 - 10/2017
2	Bovine Serum AlbuminIBA 01/2018 - 10/2003
2	AntioxidantsIBA 10/2017 - 03/2013
2	Abatacept (Orencia)FDA Link 04/2016 - 01/2014
2	AutoantibodiesIBA 10/2015 - 08/2011
2	Immunoglobulin G (IgG)IBA 05/2015 - 08/2011
2	Type 1 Angiotensin ReceptorIBA 11/2014 - 10/2004
2	bardoxolone methylIBA 02/2014 - 03/2013
2	Ramipril (Altace)FDA LinkGeneric 01/2013 - 11/2011
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2010 - 01/2007
2	candesartanIBA 11/2010 - 06/2006
2	Rosuvastatin Calcium (Crestor)FDA Link 11/2010 - 01/2007
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 12/2009 - 05/2007
2	FicollIBA 11/2009 - 01/2007
2	Endothelin Receptors (Endothelin Receptor)IBA 08/2008 - 12/2002
2	NPHS2 proteinIBA 05/2008 - 06/2004
2	Transcription Factors (Transcription Factor)IBA 05/2008 - 01/2004
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 05/2007 - 05/2007
2	Protein Isoforms (Isoforms)IBA 02/2006 - 10/2004
2	Enalapril FDA LinkGeneric 01/2006 - 11/2004
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2004 - 09/2003
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2004 - 01/2004
2	Arginine (L-Arginine)FDA Link 03/2004 - 09/2003
2	Messenger RNA (mRNA)IBA 10/2003 - 07/2003

Therapy/Procedure

21	Therapeutics 01/2021 - 07/2003
7	Kidney Transplantation 01/2020 - 11/2008
3	Transplantation 01/2020 - 08/2008
3	Organ Transplantation 01/2008 - 04/2000
2	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2017 - 05/2014
2	Lasers (Laser) 12/2009 - 05/2007